Unlocking the Power of NAD+: A Comprehensive Guide
- Gary M. Rudashevsky, NP
- Jun 9, 2025
- 4 min read
Understanding the Importance of NAD+
NAD+ is essential for cellular energy, metabolism, DNA repair, and longevity.
Levels drop by up to 50% with age, contributing to fatigue, brain fog, and weight gain.
Injections offer superior absorption compared to oral supplements.
Clinical studies support safety and potential benefits for energy, insulin sensitivity, and cognitive function.
Mild side effects only (e.g., soreness, fatigue); always administered under medical supervision.
What Is NAD+ and Why Should You Care?
Nicotinamide Adenine Dinucleotide—better known as NAD+—isn’t just a trendy buzzword. It’s a coenzyme that powers nearly every essential function in your body, including:
Cellular energy production (ATP)
DNA repair and protection
Mitochondrial function
Healthy aging
Gene expression
Brain and metabolic performance
Research shows that NAD+ levels can drop by as much as 50% by middle age. This decline is linked to:
Fatigue
Brain fog
Weight gain
Slower recovery
Poor metabolic function
What Causes NAD+ Levels to Fall?
Several factors contribute to the decline of NAD+ levels:
Aging
Stress and poor sleep
Alcohol or medications
Mitochondrial dysfunction
Inflammation and chronic illness
The Science Behind NAD+ Injections
Why Injections Are Superior to NAD+ Supplements
💊 Pills vs. 💉 Injections
Oral supplements are popular, but most NAD+ capsules are poorly absorbed in the gut. NAD+ injections, on the other hand, bypass digestion entirely—delivering active NAD+ directly into your bloodstream or tissues.
Key Advantages of Injections:
Higher bioavailability
Faster onset of effects
More predictable results
Controlled dosing and purity under medical supervision
Benefits of NAD+ Injections (Backed by Research)
⚡ Energy & Mitochondrial Support
NAD+ is critical for ATP production. In animal and human studies, restoring NAD+ levels has shown to:
Boost muscle endurance
Enhance cardiovascular health
Increase mitochondrial efficiency
🔥 Metabolic Health
NAD+ injections may help:
Normalize insulin sensitivity
Reduce inflammation in fat cells
Improve adiponectin (fat-burning hormone)
🧠 Cognitive Function
NAD+ supports:
Neuroprotection against age-related decline
Mental clarity and reduced brain fog
Memory and cognition improvements in Alzheimer’s disease models
🧬 Anti-Aging & Tissue Repair
Higher NAD+ levels are linked to:
Improved DNA repair
Retinal regeneration
Faster recovery in liver, kidney, and heart tissue
Cellular longevity and resilience
Are NAD+ Injections Safe?
Yes—when administered correctly under medical supervision.
✅ Clinical Data Shows:
No major adverse events reported
Most side effects were mild and temporary
Common Side Effects (If Any):
Slight fatigue
Localized soreness at the injection site
Mild headaches or sleep changes
Important: Always receive NAD+ injections from a licensed provider using pharmaceutical-grade ingredients.
Who Should Consider NAD+ Therapy?
NAD+ injections may be right for you if you’re experiencing:
Ongoing fatigue or low motivation
Brain fog or poor concentration
Slower metabolism or stubborn weight gain
Recovery from illness, travel, or high stress
Interest in anti-aging, longevity, or biohacking
⚠️ NAD+ is not recommended for:
Those with active cancer, severe kidney or liver disease
Individuals allergic to NAD+ components
What to Expect with NAD+ Injections at Medical Specialists
🩺 1. Initial Medical Evaluation
We’ll review your labs, health history, goals, and current medications to determine if NAD+ is appropriate.
💉 2. Customized Dosing
A common starting protocol is:
50 mg subcutaneously, once per week
Increased gradually based on tolerance and response
📊 3. Progress Monitoring
We track:
Energy levels
Focus and mood
Sleep quality
Physical recovery
Injections vs. NAD+ IV Therapy
NAD+ Injections
5-minute appointment
Can be done at home (with prescription)
More affordable (~$400–500/month)
NAD+ IV Therapy
Higher dose potential
Requires 1–3 hour in-clinic sessions
Costs $1,000+ per session
For most people, injections offer more convenience and accessibility—with similar results over time.
What the Research Still Doesn’t Prove (Yet)
While NAD+ shows enormous promise, large-scale human studies are still ongoing.
Existing data is positive—but mostly based on animal models, small human trials, and observational studies. At Medical Specialists, we emphasize science-backed therapies, paired with lifestyle optimization, diagnostics, and professional oversight.
Choosing the Right NAD+ Provider
Before starting NAD+ therapy, ask:
✅ Is this being prescribed by a licensed medical provider?
✅ Are pharmaceutical-grade ingredients being used?
✅ Are labs and health history reviewed before starting?
✅ Is ongoing supervision included?
Don’t buy NAD+ injections online or take oral supplements without guidance. Work with professionals who know the science and the risks.
Ready to Explore NAD+ Injections in Edina, MN?
At Medical Specialists MN, we take a modern, science-based approach to regenerative health and hormone optimization. If you're curious about NAD+ therapy, our expert team can guide you safely—whether you're looking to boost energy, sharpen focus, or support healthy aging.
📍 Located in Edina, MN – Serving Minneapolis, St. Paul, and the Twin Cities
📞 Call (952) 225-5400 🌐 www.medicalspecialistsmn.com
This content is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before beginning NAD+ therapy.
